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NAD+ declines naturally with age, contributing to reduced cellular function, decreased energy production, and impaired DNA repair
The Framingham Offspring study found that 39% of the general population may be in the low normal + deficient B12 blood level range
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Up to 20% of people over 60 may become deficient according to UCLA Health (2022), and the National Institutes of Health estimates that 10 to 30% of older adults cannot absorb naturally occurring vitamin B12 from food
Buying a low-dose supplement or taking several overlapping products is not the same as following a clinically appropriate replacement plan
References Markle HV, Greenway DC
