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PubMed, Zhang, Xiaofeng, et al
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Furthermore, butyrate specifically binds to and activates GPR109A/GPR43 receptors, triggering protein kinase C (PKC) signaling that leads to the activation of the antioxidant transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) (Guo et al., 2020) (Figure 1A)
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