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TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation

And then the benefits seem to plateau

Reduction of Dark Spots and Acne Marks : The treatment is often chosen to reduce the appearance of dark spots, post-acne marks, and acne-related discoloration

In patients with SURF-1 mutations, symmetrical involvement of the bilateral brainstem and subthalamic nuclei is common, and some patients exhibit basal ganglia abnormalities

see Figure 6

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