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Because Thymosin Beta-4 is present throughout the body, TB-500 is studied for whole-body cell migration and regeneration rather than purely local repair

BPC-157 is not FDA-approved, and patients should only use it under medical supervision

While early and smaller trials showed promising fat-loss effects, the largest Phase IIb trial did not achieve statistical significance in humans for its primary endpoint of weight reduction, which led to the program being discontinued

The distinction most people miss: short-term tolerability is not the same as long-term safety

Site rotation is medically recommended to prevent lipohypertrophy (localized fat accumulation), fibrosis, or tissue damage from repeated needle trauma

Relatively little of this impact is scientifically proven, but the potential downsides are minimal and the upsides are significant, so many people find it worth trying