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Subsequent work established that the same sequence exists in human plasma, saliva, and urine at concentrations that decline with age, and that the sequence is found as a subfragment of the alpha-2 chain of type I collagen, which means GHK is released into the tissue environment when collagen breaks down

Once reconstituted, the solution remains stable under refrigerated conditions for the duration of its intended shelf life

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Colour is the most immediately useful signal: copper(II) peptide complexes are blue to violet, and the intensity and hue relate to the coordination environment, so a marked change in colour genuinely indicates that something about the complex has altered