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Tat-induced oxidative stress, DNA damage, and chromosomal aberrations are novel oncogenic factors promoting B-cell lymphomas in HIV-1 infection 123

We propose ALCAR as a new possible repurposed agent for cancer prevention and interception, similar to aspirin, metformin or beta-blockers

International Association of Providers of AIDS Care

Alternative Medicine Review, 3(3), 187-198

All experiments were conducted at least two times

PIK3CA -MT HCT116 colorectal cancer cells exhibit a decrease in intracellular glutamine levels and increase in ROS levels upon treatment with glutamine-targeted drugs We further investigated the mechanism underlying the aspirin-induced elevation of intracellular glutamine levels in PIK3CA -MT colon cancer cells under hypoxia