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Moradi-Kor N, Dadkhah M, Ghanbari A, Rashidipour H, Bandegi AR, Barati M, et al
Both the 9 mg and 12 mg weekly doses met all primary and key secondary endpoints
Semaglutide is a GLP-1 (Glucagon-Like Peptide-1) receptor agonist that mimics a natural hormone in the body
it is costly and may carry risks of headaches, anaphylactic shock, meningitis, or infectious disease
Conclusions Oral semaglutide at a dose of 25 mg once daily resulted in a greater mean reduction in body weight than placebo in participants with overweight or obesity
The outcome could shape future drug marketing , FDA warning requirements , and patient safety protections for years to come.
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