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Paracetamol is a suitable first-line alternative for mild to moderate pain, whilst topical NSAIDs (such as ibuprofen gel) provide localised relief for musculoskeletal conditions with minimal systemic absorption and reduced gastrointestinal risk compared to oral NSAIDs
Statistical significance was assessed using one-way ANOVA
Cryotherapy for small joints like hands and wrists works well with ice water immersion or specialized cold wraps
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