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They protect HaCaT cells from oxidative stress damage caused by H 2 O 2

Citation85,Citation86 The selective membrane disruption action is similar to its bactericidal action: the cationic AMPs directly interact with the cancer cell membrane through electrostatic attraction to form transient pores and destroy the integrity of the cell membrane and finally cause cell death

In addition, it was noted that both BP and DOX work synergistically and upregulate the expression of apoptotic genes and proteins and eventually decrease the volume of tumor cells while decreasing the level of nitric oxide and estrogen and downregulating the level of pro-inflammatory cytokines in mice models with induced 4 T1 breast tumors

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