Frontiers in Endocrinology, 11, 178
To overcome this limitation, synthetic GLP-1 analogues like semaglutide, Wegovy, Ozempic, Rybelsus, Retatrutide, and Tirzepatide have been developed
Tirzepatide (MOUNJARO) is a once-weekly subcutaneous injectable agent first authorized for T2DM and later extended to the management of obesity or overweight with at least one weight-related comorbidity, thereby aligning its therapeutic scope with subcutaneous liraglutide and semaglutide [34,35,36]
This strategy targets both the physical and mental aspects of pediatric obesity, addressing not only weight loss itself, but the intrusive thoughts about food and hunger that comprise food noise. She also notes that CHLAs patient population, primarily publicly insured people of color, have different barriers to care than the patient populations usually included in pediatric obesity research
Zatorski H, Saaga M, Fichna J
This makes it easier to manage calorie intake and achieve a calorie deficit, which is crucial for losing weight