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Human timelines are less defined
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It was first isolated from human plasma, where it naturally occurs at concentrations of around 200 ng/mL at age 20, declining to approximately 80 ng/mL by age 60
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They monitor for improved sleep architecture (via wearable/tracking), morning recovery feeling, and reduction in stress hormones or improved hormone balance (if they have access to such measures)
Funding for dissemination of this work was awarded as part of the HDR UK publication fund
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