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PDHX acetylation facilitates tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression
For example, not including inflammatory markers such as IL-1, IL-6, or C-reactive protein (CRP), markers of metabolic risk such as C-peptides or insulin resistance index, and oxidative stress markers such as plasma isoprostanes limited the interpretation of our findings to support the antioxidant compensation hypothesis, in particular in subjects with OWOB
At the molecular level, the thiol group of the supplemented glutathione acts as a highly efficient electron donor
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