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Pioglitazone Pioglitazone is extensively metabolized by hydroxylation and oxidation

N Engl J Med 2017;377:122839.PubMedPMC 69

doi: 10.1161/CIRCULATIONAHA.118.036418 42 MarsoS

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(More information) While results of intervention studies are mixed, some evidence suggests that treatment with citicoline (a choline derivative) may be useful to improve retinal function in some patients with glaucoma