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Research has even shown potential benefits in addiction (reduced alcohol and substance cravings) and improved cognitive function

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If you're not experiencing meaningful appetite reduction after three to four weeks, your dose may need to be increased, but this decision should be made in consultation with your provider, not based on burping frequency

Indeed, Klotho modulates calcium and phosphate metabolism primarily via FGF23-dependent mechanisms as well as non-FGF23-dependent mechanisms (Kawai, 2016