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Marrs KA (1996)
rather, it relies on the adequate provision of biochemical precursors and cofactors required to sustain and optimize this intrinsic detoxification system
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Also, the male KO mice had an increased CYP1A2 (Part of the P450 enzyme family that are responsible for a large part of detoxification), however this wouldnt really explain the differences seen in Figure 2 (side-note: Ok, this last part was extremely geeky and I try to make this as mainstream as possible
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Cells were washed to remove viral particles and transduced cells were selected in the presence of 1 g/ml puromycin (Sigma-Aldrich, P8833) for at least 96 h
