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Take home message Most people lose about 2-3% of their body weight while they are on the lowest 1.5 mg dose

Large clinical trials have reinforced these recommendations

some only provide documentation for reimbursement

The medication works by mimicking the incretin hormone GLP-1, which enhances insulin secretion, suppresses glucagon release, slows gastric emptying (though this effect may attenuate over time), and reduces appetite through central nervous system pathways

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