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In individuals exhibiting robust therapeutic outcomes, these microbial metabolites potentially initiate a complementary signaling cascade via free fatty acid receptors on enteroendocrine L-cells, thereby reinforcing host incretin pathways

Pendulum will need to produce stronger clinical evidence to maintain relevance as orally available pharmaceutical alternatives emerge

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[3] Dluski DF, Ruszaa M, Rudziski G, Poarowska K, Brzuszkiewicz K, Leszczyska-Gorzelak B