It suppresses REM sleep, fragments sleep architecture in the second half of the night, increases sympathetic nervous system activation (elevated heart rate during sleep), and worsens sleep apnea
RxSaver: Similar pricing structure
If youre going to use Dihexa anyway, this article walks through the dose ranges discussed, the timing patterns, what people report about cycling, and how to think about risk in the absence of validated guidance
This is typically a business decision about which drugs the insurer has negotiated pricing for
Here's what the current data shows: Source: TRIUMPH-4 (N=445, 12mg dose, 68 weeks) and TRIUMPH-1 (N=2,339, 80 weeks + 104-week extension)
Obvious question: for those who either cant afford lifetime GLP-1 therapy, or prefer not to live with the risk and expense, whats the post-drug alternative