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Full results were presented at the American Diabetes Associations 85th Scientific Sessions alongside the REDEFINE 1 data
Clinical trials have explored the safety profile of AOD and reported few adverse effects, such as insulin resistance or unwanted muscle growth, which are typically associated with traditional GH therapies (2)
The majority of the gold standard methodologies (e.g., electron microscopy or immunohistochemistry) visualize synapses or measure changes in pre- and postsynaptic proteins ex vivo
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Translation into clinical applications remains an unresolved question
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