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GLP-1R agonists (GLP-1RAs) function through activating GLP-1R and are primarily used in the treatment of type 2 diabetes (T2D) and obesity

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observed that the gut microbiota of diet-induced obese (DIO) mice treated with liraglutide for four weeks displayed a similar phylogenetic composition in comparison to the start of the treatment, but was characterized by a significant decrease in microbial phenotypes associated with obesity (e.g., Firmicutes Lachnospiraceae and Clostridiales ), alongside an increase in Proteobacteria (e.g., Burkholderiales bacterium YL45 ) and Akkermansia muciniphila a species largely associated with high-fibre diets and mucosal barrier health (11, 6971)

The litter born from mothers administered with resveratrol, demonstrated a significative improvement in social interaction test and repetitive behaviors

PubMed laboratory research record [PMID: 3249750] PubMed record related to this compound for laboratory literature review

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