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Decreased mRNA expression or protein levels for TGF1, TGFBR1 [41], SMAD3 [42], SMAD6 [43], and SMAD7 [41, 43] have been reported in more advanced stages of COPD or fibroblasts from COPD patients

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This is hypothesized to preserve the bodys methyl pool, which is essential for DNA methylation and epigenetic regulation

Phytosterols What they do General Phytosterols are a group of plant-derived compounds that are similar in structure to cholesterol

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