Liraglutide improves water Maze learning and memory performance while reduces hyperphosphorylation of tau and neurofilaments in APP/PS1/Tau triple transgenic mice
For oGTT and ipGTTs, mice were fasted overnight for 14 h and 2 g/kg glucose (Merck, 0.2 g/ml dissolved in 0.9% NaCl) was administered by gavage or ip injection, respectively
Nanoparticle carrier systems Lipid-based nanoparticles The design of nanoplatforms targeting GLP-1R involves considerations such as nanocarrier types, surface functionalization with targeting ligands, stimulus-responsive release mechanisms, and multifunctional integration
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NICE-approved weight management includes dietary modification, orlistat, GLP-1 receptor agonists for specific patients, and bariatric surgery for severe obesity
Liu J, Zhang M, Qin C, Wang Z, Chen J, Wang R, et al