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Sphingoid bases regulate the Sigma-1 receptorsphingosine and N,N-dimethylsphingosine are endogenous agonists

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There are additional claims pending in a separate GLP-1 MDL over vision loss

Some complaints also include eye-related allegations, including non arteritic anterior ischemic optic neuropathy claims and, in some reports, references to arteritic anterior ischemic optic events, which involve compromised blood flow to structures in the eye

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