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About this article Cite this article Handelsman, Y., Muskiet, M.H.A
The efficacy and safety appear to be equivalent between the two methods, even though the interpretation is limited by the small numbers and heterogeneity of selected trials
M., Reddy, K
The shot goes under the skin (subcutaneous)
It reduces blood glucose levels and stimulates GLP-1 secretion via a G-protein mediated pathway, while also enhancing the insulin secretion through the modulation of ATP-dependent potassium channel thereby increasing calcium influx from intracellular reserves
Key Takeaways Tesamorelin has FDA approval backed by two Phase 3 RCTs showing roughly 15 to 18 percent visceral fat reduction at 26 weeks in HIV-lipodystrophy patients (Falutz et al., 2007, 2010)
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