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Specific substrate binding is enabled by Arg 166 , Arg 284 and Ser 447 while dual cofactor specificity for NAD + and NADP + is mediated by Asn 184
Therefore, transporters located in organelle membranes must operate to fulfill the intracellular traffic of carnitine and its derivatives
J., Girard, B., Pouliquen, P., Cooper, H., and Creuzot-Garcher, C
IM injections may help maintain adequate levels in these patients
We first examined the concentration-dependent effect of PFOS on mitochondrial bioenergetics and discovered that an increase in the PFOS concentration from 100 to 200 M significantly decreased mitochondrial bioenergetics, as evidenced by the decreased ATP production, maximal respiration and spare respiratory capacity, and increased proton leakage (Fig