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MOTS-c dosing in clinical settings is based on extrapolation from mouse pharmacology (5 mg/kg in mice, allometrically scaled)

Dark red and light red mark cysteine residues with 2-fold and 1.5-fold reactivity changes compared to protein expression, respectively

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Increasing bioavailability of (R)-alpha-lipoic acid to boost antioxidant activity in the treatment of neuropathic pain

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