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Some individuals view lower doses as a way to support short- or medium-term metabolic goals rather than committing to higher doses long term
GLP-1 receptor agonists enhance glucose-dependent insulin secretion and promote satiety, whilst SGLT2 inhibitors block renal glucose reabsorption causing urinary glucose excretion
You reduce the dose AND extend the interval simultaneously
For many people, the 14-15% average weight loss with semaglutide, combined with its better tolerability profile, represents the right balance of benefit and risk
Doesn't work on pigmentation and dark spots
But that is only part of what metformin does
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