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SLU-PP-332 SLU-PP-332 is a synthetic small-molecule ERR (estrogen-related receptor) pan-agonist under investigation for its role in mitochondrial biogenesis, skeletal muscle fiber-type switching, and metabolic regulation

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By selectively inhibiting NNMT an enzyme central to energy regulation and fat metabolism this compound has demonstrated, in preclinical studies, the capacity to elevate intracellular NAD and SAM levels, suppress lipid accumulation in adipocytes, and reduce white adipose tissue mass in diet-induced obese mouse models

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Scientists want to know if 5-Amino-1MQ can block NNMTs activity to tackle the problem

(3) Kannt A, et al