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CSCs have been linked to chemoresistance in cancer patients, which accounts for 90% of treatment failures
When do relationship starts to fall apart, when communication starts to fall apart and break down, right
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The appropriate response to that uncertainty is not to abandon the compound but to use it within a structured clinical framework: defined goals, evidence-appropriate dosing, quality-assured sources, systematic monitoring, and ongoing reassessment as the science matures
Two main downstream pathways PI3K Akt mTOR
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