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For days 48 of differentiation, cells were maintained in growth medium supplemented with 5 g ml 1 insulin until collection

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Ten-eleven Translocation (TET) enzymes converts methylcytosine (m 5 C) to hydroxymethylcytosine (hmC), which is not recognized by Dnmt1, it is believed to exclude maintenance methylation allowing for passive demethylation, and it is an intermediate in the active conversion of m 5 C to cytosine (C) 27

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To view a copy of this licence, visit About this article Cite this article Kozlovich, S.Y., Pan, A.Y., McIntosh, J.J