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It plays a central role in: Neutralizing reactive oxygen species (free radicals) Supporting liver detoxification pathways Maintaining immune and mitochondrial health Protecting proteins and DNA from oxidative damage Low glutathione levels or an impaired glutathione system are associated with increased oxidative stress, which contributes to fatigue, inflammation, and slower recovery
Current medicinal chemistry, 29(18), 33003323
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This helps explain why patients with extensive surgical trauma or prolonged ischemia often develop a systemic inflammatory response that parallels septic shock, even in the absence of infection (54)
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