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Obes Pillars 2025;15:100175
Mechanistic investigations highlight that GLP-1 RAs have not just weight loss, but also anti-inflammatory and metabolic properties, suggesting their efficacy against several chronic conditions
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4 Obesity is one of the strongest modifiable risk factors for AF
For those with hypothyroidism , stable thyroid hormone replacement is beneficial before starting Mounjaro, as uncontrolled hypothyroidism can affect metabolic parameters and complicate diabetes management
Neural circuitry-based studies highlight cortical disinhibition as a critical factor in schizophrenia affecting GABAergic interneurons (parvalbumin, SOM/NPY/CCK/expressing interneurons)
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