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Pregnancy Support: Ensures maternal and fetal health (as directed by physicians)

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A scatter plot was generated using RStudio with the ggplot2 package

Consult the label: Wegovy labeling recommends stopping semaglutide at least 2 months before a planned pregnancy. Understand drug clearance: It generally takes about five half-lives for substantial elimination ( 57 weeks for semaglutide

Metformin Limited data from controlled pharmacokinetic studies of metformin in healthy elderly subjects suggest that total plasma clearance of metformin is decreased, the half-life is prolonged, and Cmax is increased, compared to healthy young subjects

(PubMed) Higashi Y, Noma K, Yoshizumi M, Kihara Y