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[78] revealed that 2550 g/mL Am-EVs in an LPS-induced Caco-2 inflammation model precisely modulated the MAPK signaling cascade through coordinated downregulation of TRIF/MyD88/p38 MAPK/FOS and upregulation of TGFBR2, leading to marked reductions in oxidative stress markers (ROS, MDA), restored catalase activity, and suppressed pro-inflammatory cytokine (TNF-/IL-1/IL-6) expression

doi:10.1038/sj.ijir.3900582

Ask a friend or family member to hold you accountable for how many ounces you drink each day

The mean annual health care costs following a diagnosis of IC/BPS are 2.0 to 2.4 times higher than age matched controls

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Absorption, bioavailability, and metabolism of flavonoids