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From Charles Darwins recognition that genetic variation fuels selection (Mcclintock, 1984), it is clear that genomes possess intrinsic mechanisms to accelerate adaptation under stress

E.ParkK

In aged animals, surgery (like abdominal exploration under anesthesia) has been shown to activate microglia and cause synaptic loss in the hippocampus, correlating with memory deficits (64)

Conformational perturbation of SARS-CoV-2 spike protein using N-acetyl cysteine: an exploration of probable mechanism of action to combat COVID-19

Voltage-gated sodium channels

Neuromodulatory systems constitute key therapeutic targets for cognitive enhancement [223]