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Concentrations of GHK-Cu in the body decline significantly with age, from approximately 200 ng/mL in young adults to under 80 ng/mL by age 60, making topical replenishment meaningful

Clinicians must also avoid intravenous administration in the presence of severe sino-atrial, atrioventricular, or intraventricular conduction block in the absence of functional pacemaker support, as well as in classic Adams-Stokes or Wolff-Parkinson-White syndromes, where suppression of accessory pathways may paradoxically precipitate fatal arrhythmias

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Consistent Delivery: Provides steady, sustained peptide delivery to target tissues

& Dice, J

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