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TLRs have three domains as follows: (A) an intracellular Toll-interleukin 1 receptor (TIR) domain, which is essential for downstream signal transduction, (B) a single transmembrane domain, and (3) an extracellular domain (consisting of leucine-rich repeats) that recognizes specific PAMPs (178)

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Growth Factor Research 29-residue N-terminal fragment of human growth-hormone-releasing hormone the minimal sequence retaining full activity at the

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Similarly, Jensen et al