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How the dual GLP-1 and GIP mechanism works To understand why a dual agonist outperforms a single agonist, you need to understand what each receptor does independently and what happens when both are activated together

That mixed picture is exactly why I get bloodwork on a schedule and why a real doctor, not a wellness clinic with a sales quota, manages this

Less resistance They are less likely to promote antimicrobial resistance 9 10

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It also requires caution in patients with prior pancreatitis, severe gastroparesis, advanced diabetic retinopathy, or those on insulin and other glucose-lowering medications