Effects studied in science The primary reason for studying oral administration of GHK-Cu is its specific behavior in the gastrointestinal tract and subsequent entry into the bloodstream: Epigenetic modulation and cellular rejuvenation: Genetic studies show that GHK-Cu can control and reset the expression of more than 4,000 human genes
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In pulmonary fibrosis studies using bleomycin to induce lung injury in mice, GHK-Cu doses of 0.0026 to 0.26 mg/mL/day administered every other day reduced inflammatory cell infiltration, decreased interstitial thickness (the scarring that stiffens lung tissue), and lowered TNF-alpha and IL-6 expression
Sikiric P, Separovic J, Anic T, et al
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doi: 10.1089/acm.2011.0673