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Likewise, there is favorable evidence to support the engraftment of neural stem cells [16] or bone marrow stromal cells [17] into the lesion site

ROS play an important role in microbial decontamination either directly by inducing oxidative stress or indirectly by promoting pathogen clearance through a number of non-oxidative mechanisms, including autophagy, T-cell responses, and pattern recognition receptor signaling 44

Hence any condition potentially impairing liver and kidney statusincluding extensive PAC useshould be carefully avoided, especially in aged and comorbid population where these organs are often impaired due to pre-existing conditions

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CD8 + T cells regulate tumour ferroptosis during cancer immunotherapy