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Given the importance of hyperandrogenism-hyperinsulinemia in PCOS, most of the current therapeutic strategies aim at reducing androgen excess by improving insulin sensitivity, mainly via lifestyle changes and/or pharmacological approaches

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Switching to every-other-week dosing was never tested as a primary outcome, leaving no clinical evidence to support that approach's safety or effectiveness

Discussion To our knowledge, this is the first study to systematically assess the association between dipeptidyl peptidase-4 inhibitors and gallbladder or biliary diseases

Obesity Medicine A field of medicine that looks at and works with the behaviors, environment, genetics, nutrition, physiology and psychosocial issues that contribute to obesity