These exerkines act through autocrine, paracrine, or endocrine mechanisms to mediate inter-organ communication, playing essential roles in regulating nervous system function, attenuating neuroinflammation, and promoting neural repair (Chow et al., 2022
They are the class to consider when the goal is building or maintaining muscle rather than healing an injury
Liposomal and hydrogel carriers dramatically improve delivery to the viable epidermis and upper dermis
Many users find that their second and third cycles produce further improvement, likely because each cycle builds upon the structural gains of the previous one
The treatment ratio (2.38) is a strong effect size
However, the design of such combinatorial therapies is complicated and they are difficult to test in clinical trials