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These include: B12 levels before injection: Individuals with low B12 levels may experience a more significant and longer-lasting benefit from a B12 injection than those with normal or high levels
Maintenance dosing schedules: Weekly injections for the first few months Bi-weekly or monthly injections after that Adjusting Frequency Based on Clinical Response The B12 injection schedule might need to change based on how well the treatment works
[118] Methionine synthase [edit] Methionine synthase, coded by MTR gene, is a methyltransferase enzyme which uses the MeB 12 and reaction type 2 to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine
But we don't know what percentage makes it through, which means oral dosing is functionally equivalent to guessing
However, there are other groups of people who are more at risk of a lack of B12 in their body
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