(Previously, Ozempic was being used for weight loss but had only been approved for diabetes.) In the years following approval, a growing number of household names from Oprah to Elon Musk spoke publicly about their positive experiences using GLP-1s for weight loss
Who may prefer injections In practice, injections often suit people who want a simpler weekly routine, have trouble remembering daily tablets, or want the more established weight-loss effect of injectable semaglutide [3]
Patient safety advice includes: Maintaining good injection technique and site rotation to minimise local reactions Staying up to date with routine vaccinations, including annual influenza and pneumococcal vaccines as recommended for people with diabetes Monitoring for signs of infection and seeking prompt medical advice if concerned Following 'sick day rules' during illness maintain hydration, continue medication if possible, but temporarily pause GLP-1 treatment if unable to keep fluids down Reporting suspected side effects via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or the Yellow Card app) Patients should not discontinue their GLP-1 receptor agonist due to concerns about immune function without first consulting their prescribing clinician
doi:10.1186/s12933-018-0740-x
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