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Under high uracil misincorporation as occurs in severe folate deficiency or marked MTHFR impairment BER creates double-strand breaks when two abasic sites on opposite strands are cleaved in close proximity before repair is completed

First, this study was limited to an animal model of plateau erythrocytosis and did not include patients with plateau erythrocytosis for validation, which may vary among species

The undesirable enamine intermediate was reduced to 0.5% by using a minimal quantity of HCl generated from RhCl 3

165 The S-NO-AAT expresses a potent antimicrobial activity, inhibits cysteine proteases, and induces heme oxygenase-1 expression in hepatic ischemia-reperfusion injury in rats

They are not FDA-approved

This calibration is a clinical decision made at each session based on the current state of the skin, not a fixed protocol setting applied uniformly