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Plasma islet amyloid polypeptide (Amylin) levels and their responses to oral glucose in type 2 (non-insulin-dependent) diabetic patients

Currently most GLP-1 drugs, their name shortened from glucagon-like peptide-1 receptor agonists, cost over $1,000 a month without manufacturer discounts and are often not covered by private insurance

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GLP-1 agonists enhance insulin secretion from pancreatic beta cells only when blood glucose levels are elevated, a mechanism termed "glucose-dependent insulinotropic action." This physiological approach reduces the risk of hypoglycemia compared with sulfonylureas or exogenous insulin, though the risk increases when GLP-1 agents are combined with insulin or sulfonylureas, potentially requiring dose adjustments of these medications

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PMID: 63 LiY.BaoY.LiY.DuanX.DongS.LinJ.et al