Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases
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A number of these free radicals are formed under oxidative eustress (good stress) and distress (bad stress), where CAT could help regulate the cellular redox-oxidative status 572
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Long-term follow-up of bezafibrate treatment in patients with the myopathic form of carnitine palmitoyltransferase 2 deficiency
it was shown 30 years ago by Trojan and colleagues that this defect could be rescued in rat high grade glioma (HGG) cells by IGF-1 depletion, rendering the cells non-tumorigenic and able to induce CD8 + cytotoxic T-cell infiltration and regression of unmodified tumors in syngeneic animals 13