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Though it is naturally produced in the body, the body's supply of glutathione can be depleted due to the natural aging process, daily stress, an unhealthy diet, and environmental pollutants

Sikiric P, Hahm KB, Blagaic AB, et al

With their intentional nonadherence to oral medications leading to multiple recurrent relapses, these patients are at serious risk for neuroprogression and brain atrophic changes driven by multiple factors: inflammatory cytokines, increased cortical steroids, decreased neurotrophins, deceased neurogenesis, increased oxidative stress, and mitochondrial energy dysfunction

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10.1042/BJ20061194 Biochem

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