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Patients with EDS, especially the common hypermobile subtype (hEDS), often endure frequent joint subluxations (partial dislocations), pain, and instability that significantly impact daily life

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IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures

doi: 10.1146/annurev.bi.52.070183.003431 192 MinichD

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