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Beyond IL-23/IL-12, other interleukins contribute to UC pathogenesis: IL-6 drives acute Phase responses and Th17 differentiation through trans-signaling via soluble IL-6 receptor-gp130 complexes

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Serati AR, Motamedi MR, Emami S, et al

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The peptide is engineered with specific amino acid substitutions, including -aminoisobutyric acid (Aib) residues, along with a C20 fatty acid side-chain modification

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